Immunoinformatics Analysis of SARS-CoV-2 Isolated from Karst of Bats in Malang, Indonesia
نویسندگان
چکیده
In December 2019, cases of mysterious pneumonia were first reported in Wuhan, Initially, the diseasewas temporarily named as 2019 novel coronavirus (2019-nCoV), then WHO announced a new name onFebruary 11, 2020, namely Coronavirus Disease (COVID-19) which is caused by virus Severe AcuteRespiratory Syndrome Coronavirus-2 (SARS-CoV-2). This can be transmitted from person toperson and has spread widely China more than 190 other countries territories. Meanwhile inIndonesia, up to September 203 thousand COVID-19 found 8336 deaths. Batsact important disease reservoirs for various etiologic agents that betweenspecies, infecting humans mammals, both domestic wild. The purpose this study was analyzeSARS-CoV-2 immunoinformatics bats Karst Malang Indonesia basis making SARS-CoV-2vaccines. research method SARS-CoV-2 amino acid Malang, analyzed byimmunoinformatics. From results, it protein Karstbats antigen, non-allergen non-toxin, so they could used vaccine candidates, diagnostickits immunotherapy.
منابع مشابه
Design of a Multi-epitope Peptide Vaccine against SARS-CoV-2 based on Immunoinformatics Data
Background and purpose: In 2019, the world has witnessed the emergence of a virus that caused acute respiratory distress syndrome in human with high mortality rates (approximately 3.7%). So far, no effective treatment has been proven against COVID-19. This study aimed at designing a multi-epitope vaccine combining several T-cell and B-cell epitopes of the SARS-CoV-2. Materials and methods: Bas...
متن کاملAnalysis of Sars-CoV-2 RBD Mutations in Khuzestan Province, Iran—A Retrospective Study, 2021
Background and Objective: One of the main reasons for the ongoing pandemic is the substitutions in the Receptor binding domain(RBD), which is involved in binding to the ACE2 receptor. Methods: Oro-nasopharyngeal swabs were collected from 41 confirmed patients between September 2020 and May 2021 to analyze the mutations of SARS-CoV-2 RBD in Khuzestan Province. Bi-Directional sequencing was use...
متن کاملWhole-inactivated SARS-CoV-2 vaccines: from fear to hope
Undoubtedly, vaccination can be one of the promising approaches to control infectious diseases such as the COVID-19 pandemic. Inactivated viral vaccines have a history of "vaccine-induced enhanced disease", which may occur when neutralizing antibodies bind to viral antigens without blocking or clearing the infection. This can cause additional inflammation through the mechanisms described for ot...
متن کاملSeroprevalence of anti-SARS-CoV-2 IgG antibody in healthcare workers: A report from Rafsanjan, Iran
Background: Healthcare workers (HCWs) have a high risk of SARS-CoV-2 infection. Seroprevalence studies can provide related data on HCWs who have a history of infections. According to numerous seroepidemiological reports of COVID-19 in different groups and the lack of seroepidemiological reports of COVID-19 in HCWs in Rafsanjan, the aim of this study was to determine the SARS-CoV-2 seroprevalenc...
متن کاملanalysis of power in the network society
اندیشمندان و صاحب نظران علوم اجتماعی بر این باورند که مرحله تازه ای در تاریخ جوامع بشری اغاز شده است. ویژگیهای این جامعه نو را می توان پدیده هایی از جمله اقتصاد اطلاعاتی جهانی ، هندسه متغیر شبکه ای، فرهنگ مجاز واقعی ، توسعه حیرت انگیز فناوری های دیجیتال، خدمات پیوسته و نیز فشردگی زمان و مکان برشمرد. از سوی دیگر قدرت به عنوان موضوع اصلی علم سیاست جایگاه مهمی در روابط انسانی دارد، قدرت و بازتولید...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian journal of forensic medicine and toxicology
سال: 2021
ISSN: ['0973-9122', '0973-9130']
DOI: https://doi.org/10.37506/ijfmt.v15i2.14805